Sustainable Solutions for Global Problems
Revolutionizing Public Safety
At Limuless, we harness biotechnology to develop innovative solutions that enhance public safety. We are working on a synthetic alternative to the LAL assay, a horseshoe crab-derived test essential for FDA approval of parenteral medications and biomedical devices. With a strong commitment to sustainability, we aim to safeguard the pharmaceutical supply chain and broaden our impact to food production, including produce and pet food, to create a safer future for all.
Our Mission
The Limuless Story
The Limuless story began at Dauphin Island Sea Lab in Alabama, where CEO Jennifer Watson first encountered horseshoe crabs in Neuroscience 101 in graduate school. Fascinated by these creatures, she was inspired by a book lent to her by a teaching assistant, sparking an idea to eliminate the need for horseshoe crab blood in testing.
In 2016, Jennifer and co-founder Richard Hatcher took a leap to bring this idea to life. They moved to Nashville, where they transformed Jennifer’s great-grandmother’s attic into a molecular biology lab, and it was there that Jennifer successfully built the first protein of the LAL cascade, marking the beginning of Limuless.
Our Innovative Approach
Sustainable Solutions
​At Limuless, we’re reshaping the future of contamination testing with our groundbreaking LAL test. Unlike traditional methods, our approach removes the horseshoe crab from the production cycle, ensuring a more sustainable process. While there are recombinant alternatives to the horseshoe crab-derived LAL test on the market, the cost per assay is similar and it requires technical expertise to perform. We leverage a unique bacterial recombinant platform to exponentially grow the essential components of the LAL cascade, allowing for highly efficient production. This innovation not only enhances the accuracy of our testing but also significantly reduces production costs, making it a more accessible and eco-friendly solution for the industry.
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Sustainable
Horseshoe-crab free LAL production
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Low Production Cost
Extracellular secretion of recombinant products
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Scalable
Exponential growth of bacterial host
Key Advantages
Advantages of the Limuless product:
Precise
Increased Sensitivity
​Our product offers unmatched precision by eliminating the impurities found in horseshoe crab blood, ensuring a purer, more accurate result. Without these impurities, our test will deliver higher consistency and reliability, setting a new standard for contamination detection.
Cost-effective
High Yield
Our product is cost-effective because it is secreted from the cell, which eliminates the need to lyse cells and significantly reduces production costs. Additionally, our bacteria can produce protein at a high yield per liter, further optimizing efficiency and lowering overall expenses.
Accessible
Market Expanding
Our product's reduced cost makes it accessible to new markets, opening opportunities for testing in industries such as food production. This includes applications in pet food and fresh produce testing, where accurate contamination detection could be more widely implemented.